Computational Analysis of Self-Expanding and Balloon-Expandable Transcatheter Heart Valves

Bicuspid aortic valve (BAV) patients are usually excluded from transcatheter implantation (TAVI) as this anatomy likely leads to oval expansion. This study presents a numerical of TAVI using both self-expanding and balloon expandable heart (THV) in bicuspid with severe stenosis. The simulation framework included patient-specific the root, calcifications BAV leaflets extracted medical imaging analysis well realistic crimping deployment THV. Tissue stress highlighted local maxima contact area between inner lumen THV stent frame. Flow based on smoothed particle hydrodynamics (SPH) technique displayed at risk paravalvular leakage (PVL). These findings provide insights thus represents further step towards use in-silico for virtual planning TAVI, aiming improving not only efficacy but also exploration borderline case BAVs.